How the FeNO monitor from Bedfont Scientific Ltd. can help GP’s and patients with a more accurate diagnosis and management of asthma.
World Asthma Day, organized by the Global Initiative for Asthma
(GINA), occurs every 1st May to raise awareness and improve asthma care
around the world1. The World Health Organization (WHO) believes that
approximately 300 million people currently suffer from asthma and the
diseases is estimated to have been attributable to 383,000 deaths in
2015 alone2. NObreath® FeNO monitor, recommended by NICE2, provides GP’s
and patients with a quick and non-invasive method of measuring airway
inflammation to improve the diagnosis and management of asthma.
Typically, asthma is a chronic respiratory disease that causes
difficulty in breathing3, however, according to Asthma UK, it is the
over-simplification of asthma that leads to the over-, under-, and
mis-diagnosis of asthma. The report has sparked concerns over the number
of people not responding to medication, being misdiagnosed with asthma,
and the mis-understanding of different asthma subtypes. Bedfont has
specialised in the design and manufacture of breath analysis medical
devices for over 40 years and in 2017 their NObreath® FeNO monitor
celebrated 10 years of improving asthma management. Bedfont have been
campaigning vigorously to raise awareness of FeNO measuring and its
benefits, especially after the increasing concerns surrounding asthma.
Bedfont hopes to help improve basic asthma care and save future
lives with the NObreath®, which is also conformed to ATS and ERS
guidelines4. The NObreath® works by measuring FeNO through breath
analysis, making the process quick, simple and non-invasive for both the
GP and the patient. Interpreting FeNO levels aids in identifying
patients who do/do not require on-going treatment5 whilst also
differentiating between allergic (eosinophilic) and non-allergic
asthma6, and if used daily, FeNO measurements can help to predict
exacerbations and attacks.7
Jason Smith, Managing Director of Bedfont, says, “On November 29th 2017, NICE published the final guidelines on Asthma: diagnosis, monitoring and chronic asthma management,
to improve asthma care, which included our NObreath® FeNO monitor.
Using FeNO measurements to evaluate airway inflammation in asthma
represents a significant advance in respiratory medicine that had been
expensive to deliver in everyday practice, until now with the NObreath®.
The theme for World Asthma Day this year is ‘never too early, never too
late’ and I believe that can definitely be said about FeNO monitoring
in asthma care.”
Dr. Stephen O’Hickey, a Respiratory Consultant at Worcestershire Acute NHS Trust, comments, “FeNO
monitoring has been a big development in the management of difficult
asthma in peripheral clinics. We first chose to use the NObreath®
because we needed a cost-effective and easily portable device for
community-based clinics and it has proven to be a valuable tool in
monitoring asthma control. By assessing patient’s FeNO levels
frequently, we are able to investigate symptoms such as the cause of
coughing and identify triggers, helping us to differentiate if it is an
inflammatory or non-inflammatory subtype of asthma. This, in turn,
enables us to identify the correct inhaled corticosteroids, but also
adjust the level of medication, if needed, safely and accurately.”
REFERENCES
1. World Asthma Day [Internet]. Global Initiative for Asthma – GINA. 2018 [cited 20 April 2018]. Available from: http://ginasthma.org/wad/
2. Measuring fractional exhaled nitric oxide concentration in
asthma: NIOX MINO, NIOX VERO and NObreath | Guidance and guidelines |
NICE [Internet]. Nice.org.uk. 2014 [cited 20 April 2018]. Available
from: https://www.nice.org.uk/guidance/dg12
3. Asthma [Internet]. World Health Organization. 2018 [cited 20 April 2018]. Available from: http://www.who.int/mediacentre/factsheets/fs307/en/
4. ATS/ERS Recommendations for Standardized Procedures for the
Online and Offline Measurement of Exhaled Lower Respiratory Nitric
Oxide and Nasal Nitric Oxide, 2005; American Journal of Respiratory and
Critical Care Medicine; vol. 171: 912-930;2005
5. Andrew D. Smith, Jan O. Cowan, Sue Filsell, Chris
MacLachlan, Gabrielle Monti-Sheehan, Pamela Jackson and D. Robin Taylor.
Diagnosing Asthma: Comparisons between Exhaled Nitric Oxide
Measurements and Conventional Tests. Am J Respir Crit Care Med Vol 169.
pp 473-478, 2004.
6. Coumou HBel E. Improving the diagnosis of eosinophilic
asthma [Internet]. Taylor and Francis online. 2017 [cited 20 April
2018]. Available from: http://www.tandfonline.com/doi/full/10.1080/17476348.2017.1236688
7. Harkins M. Exhaled Nitric Oxide Predicts Asthma
Exacerbation [Internet]. Taylor & Francis. 2017 [cited 20 April
2018]. Available from: http://www.tandfonline.com/doi/abs/10.1081/JAS-120033990